Abstract Adverse effects and multidrug resistance remain significant obstacles in conventional cancer therapy.Nanomedicines, with their intrinsic properties such as nano-sized dimensions and Necklaces tunable surface characteristics, have the potential to mitigate the side effects of traditional cancer treatments.While nanomaterials have been widel
The tumour suppressor p53 is now known to be an ancient transcription factor that had already evolved interaction sites with its partner protein MDM2 at the dawn of multi-cellular eukaryotic animal life.The billion-year life history of Still Life Art the p53-MDM2 axis has permitted significant time for the proteins to integrate into a distinct rang
Background: Extracorporeal membrane oxygenation (ECMO) is a temporary mechanical support system that handles the function of the heart and/or lungs in patients with a variety of cardiac and respiratory problems.Veno-arterial ECMO is most commonly used for patients recovering from heart surgery, suffering from cardiac shock, or awaiting a heart tran
Abrupt autofocusing performance of a circular Airyprime beam (CAPB) with vortex pairs propagating in free space is investigated.Here the vortex pairs are off-axis by default.The influences of topological charges and spatial location of vortex pairs on abrupt autofocusing behaviour of a CAPB with vortex pairs are evaluated by numerical simulations.A
This article tracks the traffic of placebos, nocebos and the effects or meaning-responses that they Necklaces solicit in order to contribute to wide-ranging critiques of the curative imaginary.Moving through three realms of biomedicine (the clinic, the lab and the market), the article explores key contradictions at play within biomedicine that beco